Andrew J. Crame
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Carbohydrate Chemistry and Synthesis, Synthesis of β-Lactam Compounds, Asymmetric Synthesis and Catalysis, Advanced biosensing and bioanalysis techniques
Most-Cited Works
- → Design and Synthesis of Pyrrolidine-5,5-trans-lactams (5-Oxohexahydropyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 2. Potency and Chirality(2001)72 cited
- → Design and Synthesis of Pyrrolidine-5,5-trans-lactams (5-Oxo-hexahydro-pyrrolo[3,2-b]pyrroles) as Novel Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. 1. The α-Methyl-trans-lactam Template(2000)46 cited
- → An efficient synthesis of a chiral carbocyclic 2′-deoxyribonucleoside synthon by directed reduction(1994)16 cited
- → A short, convergent synthesis of two chiral antiviral agents, (+) carbocyclic 2′-deoxy-5-[(E)-2-bromovinyl] uridine and (+) carbocyclic 2′-deoxyGuanosine(1995)13 cited
- → Synthesis of Benzodioxinopyrroles as selective α2-adrenoceptor antagonists(1995)1 cited
- → ChemInform Abstract: An Efficient Synthesis of a Chiral Carbocyclic 2′‐Deoxyribonucleoside Synthon by Directed Reduction.(1995)
- → ChemInform Abstract: A Short, Convergent Synthesis of Two Chiral Antiviral Agents, (+)‐ Carbocyclic 2′‐Deoxy‐5‐((E)‐2‐Bromovinyl) Uridine and (+)‐Carbocyclic 2′‐Deoxyguanosine.(1996)
- → ChemInform Abstract: Stereoselective Synthesis of α‐Methyl and β‐Methyl Pyrrolidine 5,5‐trans‐Lactam (5‐Oxo‐hexahydro‐pyrrolo[3,2‐b]pyrrole) and Stereoselective Alkylation of the Strained Pyrrolidine 5,5‐trans‐Lactam Ring System.(2000)