Ligaya M. Simpkins
Bristol-Myers Squibb (United States)(US)
Publications by Year
Research Areas
Peptidase Inhibition and Analysis, Chemical Synthesis and Analysis, Neuropeptides and Animal Physiology, Diabetes Treatment and Management, Protein Hydrolysis and Bioactive Peptides
Most-Cited Works
- → Discovery and Preclinical Profile of Saxagliptin (BMS-477118): A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes(2005)619 cited
- → An MTP Inhibitor That Normalizes Atherogenic Lipoprotein Levels in WHHL Rabbits(1998)268 cited
- → Dual Metalloprotease Inhibitors: Mercaptoacetyl-Based Fused Heterocyclic Dipeptide Mimetics as Inhibitors of Angiotensin-Converting Enzyme and Neutral Endopeptidase(1997)198 cited
- → Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP)(2006)151 cited
- → Synthesis of Novel Potent Dipeptidyl Peptidase IV Inhibitors with Enhanced Chemical Stability: Interplay between the N-Terminal Amino Acid Alkyl Side Chain and the Cyclopropyl Group of α-Aminoacyl-l-cis-4,5-methanoprolinenitrile-Based Inhibitors(2004)103 cited
- → A Novel Series of Highly Potent Benzimidazole-Based Microsomal Triglyceride Transfer Protein Inhibitors(2001)61 cited
- → Dual Metalloprotease Inhibitors. 6. Incorporation of Bicyclic and Substituted Monocyclic Azepinones as Dipeptide Surrogates in Angiotensin-Converting Enzyme/Neutral Endopeptidase Inhibitors(1996)60 cited
- → Peptidomimetic Synthesis: A Novel, Highly Stereoselective Route to Substituted Freidinger Lactams(1994)55 cited
- → 1-Acyltriazoles as antiinflammatory agents(1982)55 cited
- → Phosphorus-containing inhibitors of HMG-CoA reductase. I. 4-[(2-Arylethyl)hydroxyphosphinyl]-3-hydroxybutanoic acids: a new class of cell selective inhibitors of cholesterol biosynthesis(1990)51 cited