Séan Mc Cafferty
Ablynx (Belgium)(BE)University of Arizona(US)Ghent University(BE)
Publications by Year
Research Areas
RNA Interference and Gene Delivery, Immunotherapy and Immune Responses, RNA and protein synthesis mechanisms, Virus-based gene therapy research, Viral gastroenteritis research and epidemiology
Most-Cited Works
- → N1-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice(2015)644 cited
- → mRNA therapeutics deliver a hopeful message(2018)117 cited
- → Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin(2019)81 cited
- → Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine(2019)70 cited
- → A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity(2022)54 cited
- → Bovine Embryo-Secreted microRNA-30c Is a Potential Non-invasive Biomarker for Hampered Preimplantation Developmental Competence(2019)46 cited
- → Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs(2021)44 cited
- → Comparison of the Expression Kinetics and Immunostimulatory Activity of Replicating mRNA, Nonreplicating mRNA, and pDNA after Intradermal Electroporation in Pigs(2018)33 cited
- → In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation(2020)33 cited
- → Off-Target and Tumor-Specific Accumulation of Monocytes, Macrophages and Myeloid-Derived Suppressor Cells after Systemic Injection(2018)19 cited