Jenifer Borgognoni
Granta Design (United Kingdom)(GB)
Publications by Year
Research Areas
Cancer-related Molecular Pathways, Heat shock proteins research, Computational Drug Discovery Methods, Microtubule and mitosis dynamics, Protein Structure and Dynamics
Most-Cited Works
- → 4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer(2007)442 cited
- → Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design(2009)222 cited
- → Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-d]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone(2009)173 cited
- → Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity(2011)112 cited
- → Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: Protein structure-guided design and SAR(2005)69 cited
- → Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping(2007)44 cited
- → Transient treatment with CDK inhibitors eliminates proliferative potential even when their abilities to evoke apoptosis and DNA damage are blocked(2008)17 cited
- → Context-Dependent Cell Cycle Checkpoint Abrogation by a Novel Kinase Inhibitor(2010)12 cited
- → Novel kinase profile highlights the temporal basis of context dependent checkpoint pathways to cell death(2010)
- → Orally Active 2-Amino Thienopyrimidine Inhibitors of the Hsp90 Chaperone(2009)