Jason D. Graci
PTC Therapeutics (United States)(US)
Publications by Year
Research Areas
Biochemical and Molecular Research, HIV/AIDS drug development and treatment, CRISPR and Genetic Engineering, Hepatitis C virus research, Viral Infections and Immunology Research
Most-Cited Works
- → Mechanisms of action of ribavirin against distinct viruses(2005)531 cited
- → Quasispecies, Error Catastrophe, and the Antiviral Activity of Ribavirin(2002)125 cited
- → RNA Virus Population Diversity, an Optimum for Maximal Fitness and Virulence(2014)103 cited
- → Small molecule splicing modifiers with systemic HTT-lowering activity(2021)85 cited
- → Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties(2018)82 cited
- → The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines(2020)70 cited
- → Therapeutically Targeting Rna Viruses Via Lethal Mutagenesis(2008)69 cited
- → Mutational Robustness of an RNA Virus Influences Sensitivity to Lethal Mutagenesis(2011)62 cited
- → Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues(2008)50 cited
- → Lethal Mutagenesis of Poliovirus Mediated by a Mutagenic Pyrimidine Analogue(2007)48 cited