Thomas V. Riera
Epizyme (United States)(US)
Publications by Year
Research Areas
Cancer-related gene regulation, Epigenetics and DNA Methylation, Biochemical and Molecular Research, Cytomegalovirus and herpesvirus research, Sirtuins and Resveratrol in Medicine
Most-Cited Works
- → SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity(2012)363 cited
- → Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss(2019)338 cited
- → SIRT1 Activation by Small Molecules(2010)213 cited
- → Crystallographic structure of a small molecule SIRT1 activator-enzyme complex(2015)198 cited
- → Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound(2015)134 cited
- → Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma(2017)133 cited
- → Cryptosporidium parvum IMP Dehydrogenase(2004)94 cited
- → Targeting a Prokaryotic Protein in a Eukaryotic Pathogen: Identification of Lead Compounds against Cryptosporidiosis(2008)85 cited
- → Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor(2015)83 cited
- → The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity(2010)66 cited