Jean E. Bemis
Catabasis Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Sirtuins and Resveratrol in Medicine, Biochemical effects in animals, Synthesis and biological activity, Protein Kinase Regulation and GTPase Signaling, Autophagy in Disease and Therapy
Most-Cited Works
- → Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes(2007)1,679 cited
- → A protein deacetylase SIRT1 is a negative regulator of metalloproteinase‐9(2009)223 cited
- → Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes(2009)204 cited
- → Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3(2009)148 cited
- → Discovery of Imidazo[1,2- b ]thiazole Derivatives as Novel SIRT1 Activators(2009)117 cited
- → Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activators(2008)90 cited
- → Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity(2006)67 cited
- → Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR(2007)48 cited
- → Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties(2007)41 cited
- → Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid(2016)26 cited