Shigemitsu Matsumoto
Takeda (Japan)(JP)
Publications by Year
Research Areas
Epigenetics and DNA Methylation, Crystallization and Solubility Studies, Polyamine Metabolism and Applications, X-ray Diffraction in Crystallography, Crystallography and molecular interactions
Most-Cited Works
- → Cyclization Reactions of Homopropargyl Azide Derivatives Catalyzed by PtCl4in Ethanol Solution: Synthesis of Functionalized Pyrrole Derivatives(2006)107 cited
- → New Synthetic Method for Indole-2-carboxylate and Its Application to the Total Synthesis of Duocarmycin SA(2004)65 cited
- → Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors(2013)55 cited
- → Inhibition of KDM1A activity restores adult neurogenesis and improves hippocampal memory in a mouse model of Kabuki syndrome(2021)43 cited
- → Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication(2017)38 cited
- → LSD1 enzyme inhibitor TAK-418 unlocks aberrant epigenetic machinery and improves autism symptoms in neurodevelopmental disorder models(2021)37 cited
- → Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase(2020)30 cited
- → Design, synthesis, and structure–activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects(2022)18 cited
- → New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase(2020)16 cited
- → The optimization for cyclization reaction of 2-(2-carbomethoxyethynyl)aniline derivatives and formal synthesis of pyrroloquinoline quinone and its analogue utilizing a sequential coupling-cyclization reaction(2005)14 cited