C.K. Allerston
Loxo Oncology at Lilly (United States)(US)
Publications by Year
Research Areas
DNA Repair Mechanisms, Biochemical and Molecular Research, Cancer-related Molecular Pathways, CRISPR and Genetic Engineering, Angiogenesis and VEGF in Cancer
Most-Cited Works
- → Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction(2010)195 cited
- → Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes(2015)92 cited
- → Pirtobrutinib preclinical characterization: a highly selective, non-covalent (reversible) BTK inhibitor(2023)86 cited
- → Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase(2013)81 cited
- → Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations(2017)60 cited
- → Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties(2017)56 cited
- → Characterization of the Human SNM1A and SNM1B/Apollo DNA Repair Exonucleases(2012)54 cited
- → Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev(2015)51 cited
- → Identification of LACTB2, a metallo-β-lactamase protein, as a human mitochondrial endoribonuclease(2016)47 cited
- → Improved genetically-encoded, FlincG-type fluorescent biosensors for neural cGMP imaging(2013)46 cited