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Kalkunte S. Srivenugopal | doi.page

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Kalkunte S. Srivenugopal

Texas Tech University(US)Texas Tech University Health Sciences Center(US)

Publications by Year

Research Areas

Epigenetics and DNA Methylation, Glioma Diagnosis and Treatment, Cancer-related Molecular Pathways, DNA Repair Mechanisms, Cancer, Hypoxia, and Metabolism

Most-Cited Works

→ Ubiquitination-Dependent Proteolysis of O6-Methylguanine-DNA Methyltransferase in Human and Murine Tumor Cells following Inactivation with O6-Benzylguanine or 1,3-Bis(2-chloroethyl)-1-nitrosourea(1996)221 cited
→ Human p53 Is Inhibited by Glutathionylation of Cysteines Present in the Proximal DNA-Binding Domain during Oxidative Stress,(2007)196 cited
→ A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care(2013)165 cited
→ Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA(2002)162 cited
→ Targeting MDM2-p53 Interaction for Cancer Therapy: Are We There Yet?(2014)143 cited
→

Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage

(2013)

120 cited

→ The Process and Regulatory Components of Inflammation in Brain Oncogenesis(2017)108 cited

→ Nuclear magnetic resonance studies of polyamine binding to a defined DNA sequence(1985)101 cited

→ The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models(2014)98 cited

Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents.(2001)