Jennifer Duffy
Takeda (United States)(US)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Cancer-related Molecular Pathways, Microtubule and mitosis dynamics, DNA Repair Mechanisms, Autophagy in Disease and Therapy
Most-Cited Works
- → A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment(2018)441 cited
- → 577 Characterization of the cellular mechanism of action of the first in class investigational inhibitor of the Ubiquitin Activating Enzyme, MLN7243(2014)8 cited
- → MLN4924, a Potent and Novel Small Molecule Inhibitor of Nedd8 Activating Enzyme, Induces DNA Re-Replication and Apoptosis in Cultured Human Tumor Cells(2008)4 cited
- → Abstract A164: The small molecule UAE inhibitor TAK-243 (MLN7243) prevents DNA damage repair and reduces cell viability/tumor growth when combined with radiation, carboplatin and docetaxel(2015)3 cited
- → Abstract 3719: TAK-243, a small molecule inhibitor of the ubiquitin activating enzyme (UAE), disrupts DNA damage repair and sensitizes tumor cells and xenografts to ionizing radiation(2016)1 cited
- → Cellular and biochemical characterization of an inhibitor of the Ubiquitin Activating Enzyme (UAE)(2011)1 cited