Daniel W. Summers
Universidade Estadual de Campinas (UNICAMP)(BR)
Publications by Year
Research Areas
Heat shock proteins research, Endoplasmic Reticulum Stress and Disease, Nerve injury and regeneration, Prion Diseases and Protein Misfolding, Protein Structure and Dynamics
Most-Cited Works
- → The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration(2017)616 cited
- → Sarm1-Mediated Axon Degeneration Requires Both SAM and TIR Interactions(2013)394 cited
- → Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism(2016)332 cited
- → TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes(2018)250 cited
- → Mitochondrial Dysfunction Induces Sarm1-Dependent Cell Death in Sensory Neurons(2014)188 cited
- → Gene therapy targeting SARM1 blocks pathological axon degeneration in mice(2019)153 cited
- → MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2(2017)150 cited
- → SARM1-specific motifs in the TIR domain enable NAD + loss and regulate injury-induced SARM1 activation(2016)141 cited
- → Transcription errors induce proteotoxic stress and shorten cellular lifespan(2015)102 cited
- → Palmitoylation enables MAPK-dependent proteostasis of axon survival factors(2018)88 cited