Jason G. Kettle
AstraZeneca (United Kingdom)(GB)Target (United States)(US)AstraZeneca (Netherlands)(NL)AstraZeneca (Singapore)(SG)Peacocks Medical Group (United Kingdom)(GB)AstraZeneca (Poland)(PL)
Publications by Year
Research Areas
Gastrointestinal Tumor Research and Treatment, Platelet Disorders and Treatments, Glioma Diagnosis and Treatment, Quinazolinone synthesis and applications, HER2/EGFR in Cancer Research
Most-Cited Works
- → Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia(2018)480 cited
- → Discovery of 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an Orally Bioavailable, Potent Inhibitor of Akt Kinases(2013)213 cited
- → Designing novel building blocks is an overlooked strategy to improve compound quality(2014)204 cited
- → Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell Survival(2016)135 cited
- → Synthesis of brevetoxin sub-units by sequential ring-closing metathesis and hydroboration(1997)131 cited
- → Enantioselective synthesis of medium-ring sub-units of brevetoxin A by ring-closing metathesis(1997)