Ashley Burke
Novartis (United States)(US)
Publications by Year
Research Areas
Microbial metabolism and enzyme function, Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Epigenetics and DNA Methylation, Hemoglobinopathies and Related Disorders
Most-Cited Works
- → Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex(2019)249 cited
- → A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin induction(2024)73 cited
- → A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner(2025)11 cited
- → Comparing hydrazine-derived reactive groups as inhibitors of quinone-dependent amine oxidases(2017)10 cited
- → Aged blood inhibits hippocampal neurogenesis and activates microglia through VCAM1 at the blood-brain barrier(2018)8 cited
- → Bifunctional Molecular Probes for Activity‐Based Visualization of Quinone‐Dependent Amine Oxidases(2018)7 cited
- → Targeted Degradation of the Wiz Transcription Factor for Gamma Globin De-Repression(2023)7 cited
- → A cereblon (CRBN) molecular glue degrader of NIMA-related kinase 7 (NEK7) reveals a context-dependent role in NLRP3 inflammasome activation(2024)4 cited
- → The structural basis of Indisulam-mediated recruitment of RBM39 to the DCAF15-DDB1-DDA1 E3 ligase complex(2019)3 cited
- → Progress towards MAC-amnesia(2023)3 cited