A. Jestel
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, Bone Metabolism and Diseases, Melanoma and MAPK Pathways, Protein Structure and Dynamics, Enzyme Structure and Function
Most-Cited Works
- → Mediator kinase inhibition further activates super-enhancer-associated genes in AML(2015)400 cited
- → Distinct Binding Mode of Multikinase Inhibitor Lenvatinib Revealed by Biochemical Characterization(2014)268 cited
- → Structures, functions and adaptations of the human LINE-1 ORF2 protein(2023)113 cited
- → Crystal Structure of the Catalytic Domain of Human Atypical Protein Kinase C-iota Reveals Interaction Mode of Phosphorylation Site in Turn Motif(2005)98 cited
- → (1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor for the Treatment of Osteoarthritis(2012)39 cited
- → Pharmacokinetic Benefits of 3,4-Dimethoxy Substitution of a Phenyl Ring and Design of Isosteres Yielding Orally Available Cathepsin K Inhibitors(2012)22 cited
- → Macrocyclic Statine‐Based Inhibitors of BACE‐1(2007)22 cited
- → Key Factors for Successful Generation of Protein–Fragment Structures(2011)18 cited
- → High-resolution crystal structures of factor XIa coagulation factor in complex with nonbasic high-affinity synthetic inhibitors(2012)15 cited
- → Phosphorylation of the Human Full-Length Protein Kinase Cι(2008)7 cited