Christian Brendel
Boston Children's Hospital(US)Harvard University(US)Dana-Farber Cancer Institute(US)Harvard Stem Cell Institute(US)
Publications by Year
Research Areas
Virus-based gene therapy research, CRISPR and Genetic Engineering, CAR-T cell therapy research, Hemoglobinopathies and Related Disorders, RNA Interference and Gene Delivery
Most-Cited Works
- → Highly efficient therapeutic gene editing of human hematopoietic stem cells(2019)509 cited
- → Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease(2020)418 cited
- → Selective Inhibition of Tumor Growth by Clonal NK Cells Expressing an ErbB2/HER2-Specific Chimeric Antigen Receptor(2014)338 cited
- → Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome(2021)168 cited
- → Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype(2016)160 cited
- → Biochemical Correction of X-CGD by a Novel Chimeric Promoter Regulating High Levels of Transgene Expression in Myeloid Cells(2010)150 cited