Richard C.A. Isaacs
United States Department of Justice(US)Drug Enforcement Administration(US)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Cancer Treatment and Pharmacology, Organometallic Complex Synthesis and Catalysis, Catalytic Cross-Coupling Reactions, Blood Coagulation and Thrombosis Mechanisms
Most-Cited Works
- → Total Synthesis of Baccatin III and Taxol(1996)430 cited
- → The Total Synthesis of a Natural Cardenolide: (+)-Digitoxigenin(1996)94 cited
- → Cine substitution in vinylstannane cross-coupling reactions(1990)66 cited
- → Synthesis of an enantiomerically pure intermediate containing the CD substructure of taxol(1993)55 cited
- → A straightforward route to functionalized intermediates containing the CD substructure of taxol.(1992)50 cited
- → Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. implementation of P3 pyridine N-Oxides to deliver an orally bioavailable series containing P1 N-Benzylamides(2003)38 cited
- → C6 Modification of the pyridinone core of thrombin inhibitor L-374,087 as a means of enhancing its oral absorption