Timothy Spicer
Publications by Year
Research Areas
Peroxisome Proliferator-Activated Receptors, Kruppel-like factors research, Nuclear Receptors and Signaling, Receptor Mechanisms and Signaling, Peptidase Inhibition and Analysis
Most-Cited Works
- → A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding(2003)360 cited
- → Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation(2016)251 cited
- → Discovery of 4-Benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): A Novel HIV-1 Attachment Inhibitor That Interferes with CD4-gp120 Interactions(2003)206 cited
- → Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming(2020)180 cited
- → Discovery of an enzyme and substrate selective inhibitor of ADAM10 using an exosite-binding glycosylated substrate(2016)176 cited
- → Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening(2018)166 cited
- → Confirming Target Engagement for Reversible Inhibitors in Vivo by Kinetically Tuned Activity-Based Probes(2012)141 cited
- → LPCAT3 Inhibitors Remodel the Polyunsaturated Phospholipid Content of Human Cells and Protect from Ferroptosis(2022)134 cited
- → In Vitro Resistance Profile of the Human Immunodeficiency Virus Type 1 Protease Inhibitor BMS-232632(2000)132 cited
- → Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication(2016)116 cited