M.A. McDonough
Publications by Year
Research Areas
Cancer, Hypoxia, and Metabolism, Metal-Catalyzed Oxygenation Mechanisms, Epigenetics and DNA Methylation, Enzyme Structure and Function, Antibiotic Resistance in Bacteria
Most-Cited Works
- → The Obesity-Associated FTO Gene Encodes a 2-Oxoglutarate-Dependent Nucleic Acid Demethylase(2007)1,512 cited
- → The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases(2011)1,021 cited
- → Structural studies on 2-oxoglutarate oxygenases and related double-stranded β-helix fold proteins(2006)430 cited
- → Inhibition of 2-oxoglutarate dependent oxygenases(2011)382 cited
- → Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2)(2006)365 cited
- → Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity(2007)322 cited
- → Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α(2008)290 cited
- → Structural studies on human 2-oxoglutarate dependent oxygenases(2010)281 cited
- → Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)(2006)280 cited
- → Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation(2014)247 cited