Frédéric Villard
Novartis (Switzerland)(CH)
Publications by Year
Research Areas
Cell death mechanisms and regulation, NF-κB Signaling Pathways, Crystallization and Solubility Studies, Hippo pathway signaling and YAP/TAZ, Receptor Mechanisms and Signaling
Most-Cited Works
- → An automated microseed matrix-screening method for protein crystallization(2007)211 cited
- → MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans(2019)120 cited
- → Structural Determinants of MALT1 Protease Activity(2012)94 cited
- → Structure of neprilysin in complex with the active metabolite of sacubitril(2016)67 cited
- → An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient(2019)65 cited
- → A macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target(2011)56 cited
- → Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors(2019)35 cited
- → Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure(2020)29 cited
- → Purification and crystallization of dengue and West Nile virus NS2B–NS3 complexes(2006)20 cited
- → Hyperglycemia Interacts with Ischemia in a Synergistic Way on Wound Repair and Myofibroblast Differentiation(2015)19 cited