Laura A. Lettice
Institute of Genetics and Cancer(GB)
Publications by Year
Research Areas
Developmental Biology and Gene Regulation, Congenital limb and hand anomalies, Genomics and Chromatin Dynamics, Hedgehog Signaling Pathway Studies, Congenital heart defects research
Most-Cited Works
- → A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly(2003)1,193 cited
- → Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development(2012)457 cited
- → Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly(2002)456 cited
- → Whole-mount in situ hybridizationon zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes(1994)384 cited
- → Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin(2009)370 cited
- → Ribonuclease H2 mutations induce a cGAS / STING ‐dependent innate immune response(2016)233 cited
- → Point mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactyly(2007)183 cited
- → Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly(2012)160 cited
- → Cohesin is required for long-range enhancer action at the Shh locus(2022)150 cited
- → Developmentally regulated Shh expression is robust to TAD perturbations(2019)149 cited