Edward L. LeCluyse
Lifenet Health(US)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Liver physiology and pathology, Drug Transport and Resistance Mechanisms, Drug-Induced Hepatotoxicity and Protection, 3D Printing in Biomedical Research
Most-Cited Works
- → Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME(2013)1,260 cited
- → Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells(2000)989 cited
- → Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies(2007)725 cited
- → The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor That Has Diverged during Evolution(2000)558 cited
- → Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation(2001)470 cited
- → In vitro models for liver toxicity testing.(2013)449 cited