Nathalie Lecointe
Inserm(FR)
Publications by Year
Research Areas
T-cell and Retrovirus Studies, Genomics and Chromatin Dynamics, Acute Lymphoblastic Leukemia research, Immune Cell Function and Interaction, Ubiquitin and proteasome pathways
Most-Cited Works
- Two site-specific deletions and t(1;14) translocation restricted to human T-cell acute leukemias disrupt the 5' part of the tal-1 gene.(1991)
- → Expression of TAL-1 proteins in human tissues(1995)114 cited
- → Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface(2002)78 cited
- GATA-and SP1-binding sites are required for the full activity of the tissue-specific promoter of the tal-1 gene.(1994)
- → A third tal-1 promoter is specifically used in human T cell leukemias.(1992)52 cited
- → Loss of TAL-1 protein activity induces premature apoptosis of Jurkat leukemic T cells upon medium depletion.(1995)48 cited
- → Molecular analysis of an unstable genomic region at chromosome band 11q23 reveals a disruption of the gene encoding the α2 subunit of platelet-activating factor acetylhydrolase (Pafah1a2) in human lymphoma(1999)21 cited
- → Distinct DNase-I hypersensitive sites are associated with TAL-1 transcription in erythroid and T-cell lines(1994)18 cited
- → Erythroid-specific Inhibition of the tal-1 Intragenic Promoter Is Due to Binding of a Repressor to a Novel Silencer(2000)16 cited
- → Expression of orf1 from the Bacillus thuringiensis NRD-12 cry2Aa1 Operon(1999)3 cited