Takehiro Fukami
RIKEN Center for Integrative Medical Sciences(JP)
Publications by Year
Research Areas
Wnt/β-catenin signaling in development and cancer, Acute Myeloid Leukemia Research, Analytical Chemistry and Chromatography, Cancer-related gene regulation, Computational Drug Discovery Methods
Most-Cited Works
- → A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo(2013)101 cited
- → RK‐287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model(2018)77 cited
- → A System for LogD Screening of 96-Well Plates Using a Water-Plug Aspiration/Injection Method Combined with High-Performance Liquid Chromatography−Mass Spectrometry(2007)61 cited
- → Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors(2019)57 cited
- → Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer(2020)40 cited
- → High-speed solubility screening assay using ultra-performance liquid chromatography/mass spectrometry in drug discovery(2008)36 cited
- → Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways(2017)26 cited
- → Combined inhibition of XIAP and BCL2 drives maximal therapeutic efficacy in genetically diverse aggressive acute myeloid leukemia(2021)25 cited
- → (−)-Ternatin inhibits adipogenesis and lipid metabolism in 3T3-L1 cells(2009)24 cited
- → Design and Synthesis of Tranylcypromine-Derived LSD1 Inhibitors with Improved hERG and Microsomal Stability Profiles(2022)18 cited