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Barry Jones | doi.page

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Barry Jones

AstraZeneca (United Kingdom)(GB)

Publications by Year

Research Areas

Pharmacogenetics and Drug Metabolism, Computational Drug Discovery Methods, Analytical Chemistry and Chromatography, Drug Transport and Resistance Mechanisms, Statistical Methods in Clinical Trials

Most-Cited Works

→ DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS(2004)922 cited
→ The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data(1997)577 cited
→ Reproducing human and cross-species drug toxicities using a Liver-Chip(2019)455 cited
→ Lipophilicity in PK design: methyl, ethyl, futile(2001)243 cited
→ Design of drugs involving the concepts and theories of drug metabolism and pharmacokinetics(1996)235 cited
→ Speculations on the Substrate Structure-Activity Relationship (SSAR) of cytochrome P450 enzymes(1992)203 cited

→ Novel Approach To Predicting P450-Mediated Drug Metabolism: Development of a Combined Protein and Pharmacophore Model for CYP2D6(1999)

160 cited

→ Identification of the cytochrome P450 enzymes involved in the N‐demethylation of sildenafil(2001)155 cited

→ A Novel Approach to Predicting P450 Mediated Drug Metabolism. CYP2D6 Catalyzed N-Dealkylation Reactions and Qualitative Metabolite Predictions Using a Combined Protein and Pharmacophore Model for CYP2D6(1999)128 cited

→ Properties of cytochrome P450 isoenzymes and their substrates part 2: properties of cytochrome P450 substrates(1997)121 cited