Jiří Lukáš
Seagen (United States)(US)
Publications by Year
Research Areas
Cancer-related Molecular Pathways, DNA Repair Mechanisms, Ubiquitin and proteasome pathways, Cancer Research and Treatments, Thyroid Cancer Diagnosis and Treatment
Most-Cited Works
- → Cyclin D1 is a nuclear protein required for cell cycle progression in G1.(1993)1,627 cited
- → DNA damage signalling guards against activated oncogenes and tumour progression(2007)514 cited
- Aberrant expression of the p53 oncoprotein is a common feature of a wide spectrum of human malignancies.(1991)
- → Cyclin E-induced S phase without activation of the pRb/E2F pathway.(1997)380 cited
- → Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts.(1993)324 cited
- The p16-cyclin D/Cdk4-pRb pathway as a functional unit frequently altered in melanoma pathogenesis.(1996)
- → DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1.(1994)276 cited
- Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines.(1994)
- → Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.(1995)246 cited
- Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer.(1995)