Carolyn Biles
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, HIV Research and Treatment, Chemical Synthesis and Analysis, Cancer therapeutics and mechanisms, HIV/AIDS Research and Interventions
Most-Cited Works
- → Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives(2000)377 cited
- → CC-1065(NSC 298223), a potent new antitumor agent. Improved production and isolation, characterization and antitumor activity.(1981)140 cited
- → Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships of novel substituted indole analogs and the identification of 1-[(5-methanesulfonamido-1H-indol-2-yl)carbonyl]-4-[3-[(1-methylethyl)amino]pyridinyl]piperazinemonomethanesulfonate (U-90152S), a second-generation clinical candidate(1993)123 cited
- → Primary cultures of hepatocytes on human fibroblasts(1979)119 cited
- → Discovery, Synthesis, and Bioactivity of Bis(heteroaryl)piperazines. 1. A Novel Class of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors(1994)90 cited
- → Structure-Based Design of HIV Protease Inhibitors: 5,6-Dihydro-4-hydroxy-2-pyrones as Effective, Nonpeptidic Inhibitors(1996)86 cited
- Morphologic and histochemical analysis of hepatocytes transplanted into syngeneic hosts.(1980)
- → Targeting Delavirdine/Atevirdine Resistant HIV-1: Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors(1996)57 cited
- → Structure of quinomycin antibiotics.(1975)56 cited
- → (Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIV-1IIIB with reduced replication phenotypes(1996)37 cited