Lan-Zhen Wang
Newcastle University(GB)
Publications by Year
Research Areas
PARP inhibition in cancer therapy, Biochemical and Molecular Research, HIV/AIDS drug development and treatment, Cancer-related Molecular Pathways, Synthesis and Characterization of Heterocyclic Compounds
Most-Cited Works
- → Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial(2007)298 cited
- → Novel Poly(ADP-ribose) Polymerase-1 Inhibitor, AG14361, Restores Sensitivity to Temozolomide in Mismatch Repair-Deficient Cells(2004)165 cited
- → Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition(2018)143 cited
- → Novel Tricyclic Poly(ADP-ribose) Polymerase-1 Inhibitors with Potent Anticancer Chemopotentiating Activity: Design, Synthesis, and X-ray Cocrystal Structure(2002)135 cited
- → N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2(2004)122 cited
- → Searching for Cyclin-Dependent Kinase Inhibitors Using a New Variant of the Cope Elimination(2006)80 cited
- Identification of potent nontoxic poly(ADP-Ribose) polymerase-1 inhibitors: chemopotentiation and pharmacological studies.(2003)
- → Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer(2016)57 cited
- → Design, Synthesis, and Evaluation of 3,4-Dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as Inhibitors of Poly(ADP-Ribose) Polymerase(2004)45 cited
- → The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b(2012)39 cited