Niko Schmiedeberg
Publications by Year
Research Areas
Peptidase Inhibition and Analysis, Protease and Inhibitor Mechanisms, Blood Coagulation and Thrombosis Mechanisms, Melanoma and MAPK Pathways, RNA and protein synthesis mechanisms
Most-Cited Works
- → The small molecule specific EphB4 kinase inhibitor NVP-BHG712 inhibits VEGF driven angiogenesis(2010)125 cited
- → G-Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5) Agonists Reduce the Production of Proinflammatory Cytokines and Stabilize the Alternative Macrophage Phenotype(2014)93 cited
- → DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance(2024)76 cited
- → Reversible Backbone Protection Enables Combinatorial Solid-Phase Ring-Closing Metathesis Reaction (RCM) in Peptides(2001)53 cited
- → Synthesis, Solution Structure, and Biological Evaluation of Urokinase Type Plasminogen Activator (uPA)-Derived Receptor Binding Domain Mimetics(2002)42 cited
- → Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field(2023)33 cited
- → Cyclo19,31[D-Cys19]-uPA19-31 Is a Potent Competitive Antagonist of the Interaction of Urokinase-Type Plasminogen Activator with Its Receptor (CD87)(2001)32 cited
- → Epitope Mapping of Monoclonal Antibodies Directed to PAI-1 Using PAI-1/PAI-2 Chimera and PAI-1-Derived Synthetic Peptides(2000)29 cited
- → Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control(2023)27 cited
- → The Crystal Structure of Cancer Osaka Thyroid Kinase Reveals an Unexpected Kinase Domain Fold(2015)17 cited