Chase C. Smith
Massachusetts College of Pharmacy and Health Sciences(US)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Biochemical and Molecular Research, Sirtuins and Resveratrol in Medicine, Cancer Treatment and Pharmacology, Microbial Natural Products and Biosynthesis
Most-Cited Works
- → First total synthesis of taxol. 1. Functionalization of the B ring(1994)628 cited
- → First total synthesis of taxol. 2. Completion of the C and D rings(1994)521 cited
- → A Three-Hybrid Approach to Scanning the Proteome for Targets of Small Molecule Kinase Inhibitors(2004)136 cited
- → Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors(2013)80 cited
- → Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors(2013)68 cited
- → Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)(2013)41 cited
- → Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties(2013)41 cited
- → Development and use of augmented reality models to teach medicinal chemistry(2021)32 cited
- → Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility(2014)28 cited
- → Use of dicobalt hexacarbonyl-estabilized propargyl cations in intramolecular Friedel-Crafts alkylations(1990)24 cited