Huw D. Lewis
GlaxoSmithKline (United Kingdom)(GB)Age UK(GB)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Cholinesterase and Neurodegenerative Diseases, Computational Drug Discovery Methods, Neuroscience and Neuropharmacology Research, Cell Adhesion Molecules Research
Most-Cited Works
- → Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation(2015)734 cited
- → L-685,458, an Aspartyl Protease Transition State Mimic, Is a Potent Inhibitor of Amyloid β-Protein Precursor γ-Secretase Activity(2000)365 cited
- → Age-Related Impairment of Synaptic Transmission But Normal Long-Term Potentiation in Transgenic Mice that Overexpress the Human APP695SWE Mutant Form of Amyloid Precursor Protein(2001)209 cited
- → A presenilin dimer at the core of the γ-secretase enzyme: Insights from parallel analysis of Notch 1 and APP proteolysis(2003)198 cited
- → Fenton chemistry and oxidative stress mediate the toxicity of the β‐amyloid peptide in a Drosophila model of Alzheimer’s disease(2009)168 cited
- → Apoptosis in T Cell Acute Lymphoblastic Leukemia Cells after Cell Cycle Arrest Induced by Pharmacological Inhibition of Notch Signaling(2007)148 cited