Lucy C.J. Ellis
University of Dundee(GB)
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Ubiquitin and proteasome pathways, Tuberculosis Research and Epidemiology, Hepatitis B Virus Studies, Trace Elements in Health
Most-Cited Works
- → Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition(2016)234 cited
- → Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase: Structure–Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)(2017)158 cited
- → Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads againstMycobacterium tuberculosis(2016)91 cited
- → ATP-dependent transport of statins by human and rat MRP2/Mrp2(2013)74 cited
- → 2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization(2018)70 cited
- → Optimization of a “bump-and-hole” approach to allele-selective BET bromodomain inhibition(2018)50 cited
- → Formation of micronuclei in erythrocytes of the fathead minnow (Pimephales promelas) after acute treatment with mitomycin C or cyclophosphamide(2007)38 cited
- → Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani(2017)29 cited
- → Quantification of biliary excretion and sinusoidal excretion of 5(6)-carboxy-2′,7′-dichlorofluorescein (CDF) in cultured hepatocytes isolated from Sprague Dawley, Wistar and Mrp2-deficient Wistar (TR−) rats(2014)11 cited
- → Quantification of efflux by multidrug resistance-associated proteins (Mrps) in rat hepatocyte cultures(2008)1 cited