A. Ruf
Roche (Switzerland)(CH)University of Cambridge(GB)
Publications by Year
Research Areas
Enzyme Structure and Function, Cancer, Hypoxia, and Metabolism, Receptor Mechanisms and Signaling, Peroxisome Proliferator-Activated Receptors, Adipose Tissue and Metabolism
Most-Cited Works
- → A general protocol for the generation of Nanobodies for structural biology(2014)793 cited
- → Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose(2011)749 cited
- → Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase(2004)349 cited
- → Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV(2003)236 cited
- → Inhibitor and NAD+ Binding to Poly(ADP-ribose) Polymerase As Derived from Crystal Structures and Homology Modeling,(1998)202 cited
- → Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1(2012)181 cited
- → The mechanism of the elongation and branching reaction of Poly(ADP-ribose) polymerase as derived from crystal structures and mutagenesis(1998)166 cited
- → A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro(2005)154 cited
- → Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations(2009)127 cited
- → Aleglitazar, a new, potent, and balanced dual PPARα/γ agonist for the treatment of type II diabetes(2009)103 cited