Leo F. Faucette

Publications by Year

Research Areas

Metal complexes synthesis and properties, Organometallic Complex Synthesis and Catalysis, Signaling Pathways in Disease, Cancer therapeutics and mechanisms, Peptidase Inhibition and Analysis

Most-Cited Works

• → Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity(1991)516 cited
• → Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway(1999)423 cited
• → Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin.(1988)321 cited
• Evaluation of the in vivo antitumor activity and in vitro cytotoxic properties of auranofin, a coordinated gold compound, in murine tumor models.(1985)
• → Dominant Missense Mutations in a Novel Yeast Protein related to Mammalian Phosphatidylinositol 3-Kinase and VPS34 Abrogate Rapamycin Cytotoxicity(1993)276 cited
• → Antitumor activity of an allosteric inhibitor of centromere-associated protein-E(2010)254 cited
• In vivo antitumor activity and in vitro cytotoxic properties of bis[1,2-bis(diphenylphosphino)ethane]gold(I) chloride.(1986)
• → Correlation of the in vitro cytotoxic and in vivo antitumor activities of gold(I) coordination complexes(1986)227 cited
• → Rapamycin Sensitivity in Saccharomyces cerevisiae Is Mediated by a Peptidyl-Prolyl cis-trans Isomerase Related to Human FK506-Binding Protein(1991)214 cited
• → Dominant missense mutations in a novel yeast protein related to mammalian phosphatidylinositol 3-kinase and VPS34 abrogate rapamycin cytotoxicity.(1993)194 cited