Michael Flagella
Revolution Medicines (United States)(US)
Publications by Year
Research Areas
Colorectal Cancer Treatments and Studies, Ion Transport and Channel Regulation, Cancer therapeutics and mechanisms, Lung Cancer Treatments and Mutations, Ion channel regulation and function
Most-Cited Works
- → Mice Lacking the Basolateral Na-K-2Cl Cotransporter Have Impaired Epithelial Chloride Secretion and Are Profoundly Deaf(1999)396 cited
- → Effect of selective LRRK2 kinase inhibition on nonhuman primate lung(2015)364 cited
- → Phenotype Resembling Gitelman's Syndrome in Mice Lacking the Apical Na+-Cl− Cotransporter of the Distal Convoluted Tubule(1998)298 cited
- → An Increase in the Expression of Ribonucleotide Reductase Large Subunit 1 Is Associated with Gemcitabine Resistance in Non-Small Cell Lung Cancer Cell Lines(2004)281 cited
- → Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice.(2000)176 cited
- → Astrocytes from Na+-K+-Cl−cotransporter-null mice exhibit absence of swelling and decrease in EAA release(2002)173 cited
- → Severe Impairment of Salivation in Na+/K+/2Cl− Cotransporter (NKCC1)-deficient Mice(2000)163 cited
- → Discovery of Highly Potent, Selective, and Brain-Penetrable Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors(2012)161 cited
- → Discovery of Highly Potent, Selective, and Brain-Penetrant Aminopyrazole Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors(2013)123 cited
- → Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na+-K+-2Cl−cotransporter(2002)113 cited