Hannah L. Woodward
Publications by Year
Research Areas
Microtubule and mitosis dynamics, Ubiquitin and proteasome pathways, Cancer Genomics and Diagnostics, Protease and Inhibitor Mechanisms, Cancer-related Molecular Pathways
Most-Cited Works
- → Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening(2013)126 cited
- → Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders(2020)73 cited
- → Carboxylesterase Notum Is a Druggable Target to Modulate Wnt Signaling(2021)48 cited
- → High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers(2019)38 cited
- → Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4-d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine (BOS172722)(2018)33 cited
- → Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach(2016)32 cited
- → Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates: synthesis and applications of α-phosphono lactams(2007)26 cited
- → Changes in Hand Function with Age and Normative Unimpaired Scores when Measured with the Southampton Hand Assessment Procedure(2008)26 cited
- → Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy(2017)26 cited
- → Expanding the scope of fused pyrimidines as kinase inhibitor scaffolds: synthesis and modification of pyrido[3,4-d]pyrimidines(2014)23 cited