Angela Helfricht
Erasmus MC(NL)Erasmus MC Cancer Institute(NL)
Publications by Year
Research Areas
DNA Repair Mechanisms, Ubiquitin and proteasome pathways, Genomics and Chromatin Dynamics, Genetics and Neurodevelopmental Disorders, PARP inhibition in cancer therapy
Most-Cited Works
- → RNF4 is required for DNA double-strand break repair in vivo(2012)118 cited
- → WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks(2019)111 cited
- → The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80(2015)89 cited
- → Ataxin‐3 consolidates the MDC 1‐dependent DNA double‐strand break response by counteracting the SUMO ‐targeted ubiquitin ligase RNF 4(2017)79 cited
- → Ubiquitin and TFIIH-stimulated DDB2 dissociation drives DNA damage handover in nucleotide excision repair(2020)65 cited
- → Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining(2013)55 cited
- → Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome(2020)44 cited
- → DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1(2018)37 cited
- → Targeting Protein for Xenopus Kinesin-like Protein 2 (TPX2) Regulates γ-Histone 2AX (γ-H2AX) Levels upon Ionizing Radiation(2012)37 cited
- → Different SWI/SNF complexes coordinately promote R-loop- and RAD52-dependent transcription-coupled homologous recombination(2023)34 cited