J.E. Debreczeni
AstraZeneca (United Kingdom)(GB)Molecular Discovery (United Kingdom)(GB)
Publications by Year
Research Areas
Enzyme Structure and Function, Peptidase Inhibition and Analysis, Protein Kinase Regulation and GTPase Signaling, Particle physics theoretical and experimental studies, Protein Tyrosine Phosphatases
Most-Cited Works
- → The CCP4 suite: integrative software for macromolecular crystallography(2023)778 cited
- → The structure of P‐TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation(2008)349 cited
- → Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR)(2013)258 cited
- → Ruthenium Half‐Sandwich Complexes Bound to Protein Kinase Pim‐1(2006)232 cited
- → Discovery of 4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an Orally Bioavailable, Potent Inhibitor of Akt Kinases(2013)213 cited
- → Structure and Substrate Specificity of the Pim-1 Kinase(2005)199 cited