David W. Lin
Pfizer (United States)(US)
Publications by Year
Research Areas
Cyclopropane Reaction Mechanisms, Catalytic C–H Functionalization Methods, Synthesis and Catalytic Reactions, Asymmetric Synthesis and Catalysis, Marine Sponges and Natural Products
Most-Cited Works
- → Pd(II)-Catalyzed Enantioselective C–H Activation of Cyclopropanes(2011)404 cited
- → Palladium(II)-Catalyzed Enantioselective C(sp3)–H Activation Using a Chiral Hydroxamic Acid Ligand(2014)259 cited
- → Scope and Mechanism of Direct Indole and Pyrrole Couplings Adjacent to Carbonyl Compounds: Total Synthesis of Acremoauxin A and Oxazinin 3(2007)189 cited
- → Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S )-2,2-Difluorocyclopropyl)((1 R ,5 S )-3-(2-((1-methyl-1 H -pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)(2018)170 cited
- → Direct Coupling of Pyrroles with Carbonyl Compounds: Short Enantioselective Synthesis of (S)‐Ketorolac(2004)164 cited
- → Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay(2017)159 cited
- → Discovery of Tyrosine Kinase 2 (TYK2) Inhibitor (PF-06826647) for the Treatment of Autoimmune Diseases(2020)73 cited
- → Synthesis-Guided Structure Revision of the Sarcodonin, Sarcoviolin, and Hydnellin Natural Product Family(2011)57 cited
- → Convergent Synthesis and Structural Confirmation of Phellodonin and Sarcodonin ε(2013)34 cited