Hatsuo Kawada
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Chemical Synthesis and Analysis, Catalytic Cross-Coupling Reactions, PI3K/AKT/mTOR signaling in cancer, Asymmetric Hydrogenation and Catalysis
Most-Cited Works
- → Design and synthesis of a highly selective, orally active and potent anaplastic lymphoma kinase inhibitor (CH5424802)(2011)163 cited
- → Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor(2023)135 cited
- → Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets(2023)89 cited
- → 9-Substituted 6,6-Dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazoles as Highly Selective and Potent Anaplastic Lymphoma Kinase Inhibitors(2011)83 cited
- → Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799(2011)70 cited
- → Discovery of novel tetracyclic compounds as anaplastic lymphoma kinase inhibitors(2011)35 cited
- → Synthetic Studies on the Taxane Skeleton: Construction of Eight-Membered Carbocyclic Rings by the Intramolecular B-Alkyl Suzuki−Miyaura Cross-Coupling Reaction(2004)29 cited
- → Preparation of new chiral building blocks via asymmetric catalysis(2003)27 cited
- → Development of silicon-tethered anionic reaction and its application to the synthesis of chiral A-ring moieties of Taxol™(2004)21 cited
- → Lead optimization of a dihydropyrrolopyrimidine inhibitor against phosphoinositide 3-kinase (PI3K) to improve the phenol glucuronic acid conjugation(2012)16 cited