Ruby C. Chou
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Drug Transport and Resistance Mechanisms, Retinoids in leukemia and cellular processes, Pharmacological Effects and Toxicity Studies, Metabolism and Genetic Disorders
Most-Cited Works
- → Integration of in Vitro Data into Allometric Scaling to Predict Hepatic Metabolic Clearance in Man: Application to 10 Extensively Metabolized Drugs(1997)179 cited
- → The Use of Human Hepatocytes to Select Compounds Based on Their Expected Hepatic Extraction Ratios in Humans(1997)106 cited
- → A highly sensitive tool for the assay of cytochrome P450 enzyme activity in rat, dog and man(1993)101 cited
- → Pharmacokinetics of acitretin and etretinate(1998)74 cited
- → Effect of heparin or salicylate infusion on serum protein binding and on concentrations of phenytoin in serum, brain and cerebrospinal fluid of rats.(1981)61 cited
- → Pharmacokinetics of oral isotretinoin(1998)55 cited
- → Interspecies scaling of tolcapone, a new inhibitor of catechol-O-methyltransferase (COMT). Use ofin vitrodata from hepatocytes to predict metabolic clearance in animals and humans(1996)43 cited
- → Interspecies Scaling of Bosentan, A New Endothelin Receptor Antagonist and Integration of in Vitro Data into Allometric Scaling(1996)43 cited
- → Interspecies Scaling of Interferon Disposition and Comparison of Allometric Scaling with Concentration-Time Transformations(1995)40 cited
- → A new extrapolation method from animals to man: Application to a metabolized compound, mofarotene(1995)39 cited