Nicolas Soldermann
Novartis (China)(CN)
Publications by Year
Research Areas
Hippo pathway signaling and YAP/TAZ, Synthetic Organic Chemistry Methods, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Asymmetric Synthesis and Catalysis
Most-Cited Works
- → Effective “activated PI3Kδ syndrome”–targeted therapy with the PI3Kδ inhibitor leniolisib(2017)278 cited
- → Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers(2024)114 cited
- → Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors(2017)112 cited
- → Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors(2016)65 cited
- → Origins of Boat or Chair Preferences in the Ireland−Claisen Rearrangements of Cyclohexenyl Esters: A Theoretical Study(2002)45 cited
- → The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition(2022)43 cited
- → Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension(2014)41 cited
- → Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D(2010)41 cited
- → 2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes(2011)32 cited
- → Pharmacophore Mapping in the Laulimalide Series: Total Synthesis of a Vinylogue for a Late-Stage Metathesis Diversification Strategy(2006)31 cited