David Borchelt
University of Florida Health(US)University of Florida(US)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Amyotrophic Lateral Sclerosis Research, Prion Diseases and Protein Misfolding, Neurogenetic and Muscular Disorders Research, Parkinson's Disease Mechanisms and Treatments
Most-Cited Works
- → APP Processing and Synaptic Function(2003)1,609 cited
- → Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase(2003)1,581 cited
- → Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo(1996)1,483 cited
- → An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria(1995)1,432 cited
- → ALS-Linked SOD1 Mutant G85R Mediates Damage to Astrocytes and Promotes Rapidly Progressive Disease with SOD1-Containing Inclusions(1997)1,327 cited
- → BACE1 is the major β-secretase for generation of Aβ peptides by neurons(2001)1,051 cited