William Senapedis
Publications by Year
Research Areas
Nuclear Structure and Function, Cancer-related Molecular Pathways, RNA Research and Splicing, Melanoma and MAPK Pathways, Pancreatic and Hepatic Oncology Research
Most-Cited Works
- → CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications(2013)302 cited
- → Nucleo-cytoplasmic transport as a therapeutic target of cancer(2014)279 cited
- → Targeting super-enhancer-associated oncogenes in oesophageal squamous cell carcinoma(2016)234 cited
- → XPO1-dependent nuclear export is a druggable vulnerability in KRAS-mutant lung cancer(2016)208 cited
- → PAK4 inhibition improves PD-1 blockade immunotherapy(2019)156 cited
- → Dual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth(2016)141 cited
- → Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death(2016)129 cited
- → Clinical translation of nuclear export inhibitors in cancer(2014)128 cited
- → KPT-8602, a second-generation inhibitor of XPO1-mediated nuclear export, is well tolerated and highly active against AML blasts and leukemia-initiating cells(2016)121 cited
- → Clinical Implications of Targeting XPO1-mediated Nuclear Export in Multiple Myeloma(2018)117 cited