Maria S. Brown
Pfizer (United States)(US)
Publications by Year
Research Areas
Microbial Natural Products and Biosynthesis, Chemical Synthesis and Analysis, Cancer, Hypoxia, and Metabolism, Carbohydrate Chemistry and Synthesis, Amino Acid Enzymes and Metabolism
Most-Cited Works
- → Modulation of Glutamine Synthetase Adenylylation and Deadenylylation Is Mediated by Metabolic Transformation of the P II -Regulatory Protein(1971)147 cited
- → Late-Stage Microsomal Oxidation Reduces Drug–Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189(2018)38 cited
- → Metabolite regulation of the state of adenylylation of glutamine synthetase(1974)37 cited
- → Biosynthetic studies of ascomycin (FK520): formation of the (1R,3R,4R)-3,4-dihydroxycyclohexanecarboxylic acid-derived moiety(1994)33 cited
- → Late-Stage Lead Diversification Coupled with Quantitative Nuclear Magnetic Resonance Spectroscopy to Identify New Structure–Activity Relationship Vectors at Nanomole-Scale Synthesis: Application to Loratadine, a Human Histamine H 1 Receptor Inverse Agonist(2020)30 cited
- → Biosynthetic Origins of the Natural Product, Thiolactomycin: A Unique and Selective Inhibitor of Type II Dissociated Fatty Acid Synthases(2003)24 cited
- → Degradation of saxitoxin to a pyrimido [2,1-b]purine(1971)21 cited
- → Optimization of Metal Affinity Ketoreductase Immobilization for Application in Batch and Flow Processes(2022)18 cited
- → Biosynthesis of the Shikimate-derived Starter Unit of the Immunosuppressant Ascomycin: Stereochemistry of the 1,4-Conjugate Elimination.(1997)18 cited
- → Production of 6-Deoxy-13-cyclopropyl-Erythromycin B by Saccharopolyspora erythraea NRRL 18643.(1999)10 cited