Gregory S. Walker
Pfizer (United States)(US)
Publications by Year
Research Areas
Pharmacogenetics and Drug Metabolism, Analytical Chemistry and Chromatography, Metabolomics and Mass Spectrometry Studies, Drug Transport and Resistance Mechanisms, Computational Drug Discovery Methods
Most-Cited Works
- → Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors(2014)322 cited
- → The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans(2014)266 cited
- → Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials(2020)138 cited
- → Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans(2022)113 cited
- → In VitroMetabolism and Covalent Binding of Enol-Carboxamide Derivatives and Anti-Inflammatory Agents Sudoxicam and Meloxicam: Insights into the Hepatotoxicity of Sudoxicam(2008)109 cited
- → Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1(2011)102 cited
- → Identifying a Selective Substrate and Inhibitor Pair for the Evaluation of CYP2J2 Activity(2012)93 cited
- → Selective Mechanism-Based Inactivation of CYP3A4 by CYP3cide (PF-04981517) and Its Utility as an In Vitro Tool for Delineating the Relative Roles of CYP3A4 versus CYP3A5 in the Metabolism of Drugs(2012)90 cited
- → Determination of Degradation Pathways and Kinetics of Acyl Glucuronides by NMR Spectroscopy(2007)67 cited
- → Biosynthesis of Drug Metabolites and Quantitation Using NMR Spectroscopy for Use in Pharmacologic and Drug Metabolism Studies(2014)63 cited