Steven H. Spergel
Bristol-Myers Squibb (United States)(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Click Chemistry and Applications, Cytokine Signaling Pathways and Interactions, Synthesis and Biological Evaluation, Nitric Oxide and Endothelin Effects
Most-Cited Works
- → Practical olefin hydroamination with nitroarenes(2015)524 cited
- → Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165(2019)356 cited
- → Selective Itk Inhibitors Block T-Cell Activation and Murine Lung Inflammation(2004)112 cited
- → Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)(2019)87 cited
- → Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors(2006)75 cited
- → Cupric bromide mediated oxidation of 4-carboxyoxazolines to the corresponding oxazoles(1993)70 cited
- → Biphenylsulfonamide Endothelin Receptor Antagonists. 4. Discovery of N-[[2‘-[[(4,5-Dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1‘-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), A Highly Potent and Orally Active ETA Selective Antagonist(2002)62 cited
- → Synthesis and antiviral activity of novel isonucleoside analogs(1993)58 cited
- → Molecular design, synthesis, and structure–Activity relationships leading to the potent and selective p56lck inhibitor BMS-243117(2003)58 cited
- → Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties(2003)57 cited