David E. Ehmann
Takeda (United States)(US)
Publications by Year
Research Areas
Antibiotic Resistance in Bacteria, Antibiotics Pharmacokinetics and Efficacy, Cancer therapeutics and mechanisms, Microbial Natural Products and Biosynthesis, Biochemical and Structural Characterization
Most-Cited Works
- → Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor(2012)513 cited
- → Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases(2013)350 cited
- → ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii(2017)267 cited
- → Molecular Mechanisms of Sulbactam Antibacterial Activity and Resistance Determinants in Acinetobacter baumannii(2015)238 cited
- → Lysine Biosynthesis in Saccharomyces cerevisiae: Mechanism of α-Aminoadipate Reductase (Lys2) Involves Posttranslational Phosphopantetheinylation by Lys5(1999)161 cited
- → Translating slow-binding inhibition kinetics into cellular and in vivo effects(2015)149 cited
- → Aminoacyl-SNACs as small-molecule substrates for the condensation domains of nonribosomal peptide synthetases(2000)133 cited
- → The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase: Sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates(2000)110 cited
- → Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity(2011)101 cited
- → Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48(2014)100 cited