Brett Janosky
Amgen (United States)(US)
Publications by Year
Research Areas
Drug Transport and Resistance Mechanisms, Pharmacogenetics and Drug Metabolism, Ion channel regulation and function, Nicotinic Acetylcholine Receptors Study, Glioma Diagnosis and Treatment
Most-Cited Works
- → Identification of a Potent, State-Dependent Inhibitor of Nav1.7 with Oral Efficacy in the Formalin Model of Persistent Pain(2011)54 cited
- → Relationship between Passive Permeability, Efflux, and Predictability of Clearance from In Vitro Metabolic Intrinsic Clearance(2009)44 cited
- → Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant α4β2 nicotinic acetylcholine receptor potentiators(2008)29 cited
- → Differential role of P-glycoprotein and breast cancer resistance protein in drug distribution into brain, CSF and peripheral nerve tissues in rats(2014)24 cited
- → Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2(2008)19 cited
- → In vitroandin vivopharmacokinetic characterizations of AMG 900, an orally bioavailable small molecule inhibitor of aurora kinases(2011)11 cited
- → Use of uptake intrinsic clearance from attached rat hepatocytes to predict hepatic clearance for poorly permeable compounds(2012)9 cited
- → Corrigendum to “Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2” [Bioorg. Med. Chem. Lett. 18 (2008) 4267–4274](2008)
- → Erratum to “Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2” [Bioorg. Med. Chem. Lett. 18 (2008) 4267–4274](2008)