Kam Siu
Arvinas (United States)(US)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Prostate Cancer Treatment and Research, Cancer-related Molecular Pathways, Growth Hormone and Insulin-like Growth Factors, Ubiquitin and proteasome pathways
Most-Cited Works
- → PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer(2016)815 cited
- → Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1(2017)249 cited
- → A highly effective one-pot synthesis of quinolines from o-nitroarylcarbaldehydes(2006)81 cited
- → One-Pot Friedländer Quinoline Synthesis: Scope and Limitations(2010)36 cited
- → Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors(2012)20 cited
- → Conformational dynamics of Cu(i) complexes of tripodal ligands: steric control of molecular motion(2005)20 cited
- → Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1(2013)20 cited
- → Discovery of Novel Insulin-Like Growth Factor-1 Receptor Inhibitors with Unique Time-Dependent Binding Kinetics(2013)17 cited
- → Potent and selective cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors with in vivo efficacy(2010)16 cited
- → ARV-330: Androgen receptor PROTAC degrader for prostate cancer.(2016)13 cited